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Stadion Letná, Prague
Thursday 12 November, 7:45pm UK time (8:45pm in Prague)
Santi Denia worked alongside Luis de la Fuente for about 12 years in Spain's youth teams, and on Thursday his winless Czechia side host the world champions at Stadion Letná, with kick-off at 7:45pm UK time.
La Roja are already through to the quarter-finals, while the hosts sit bottom of Nations League A Group 3 on zero points after four defeats.
Czechia vs Spain preview and form guide
With no points from four games, the Czechs sit bottom of Nations League A Group 3, three behind Croatia, whom they visit on 15 November.
Denia, who took over on 31 July as the first foreign coach in the national team's history, has lost all four matches, scoring twice and conceding 10.
The side's only goals in the group came from Adam Karabec against Croatia on 26 September and Jiri Slama in Oviedo on 3 October, and Karabec is now injured.
They arrive on five straight defeats, starting with a 0-3 loss to Mexico at the World Cup, where they went out in the group stage with one point.
Denia says the aim now is to collect points rather than only competitive performances, and he has asked why his players could not beat La Roja.
La Roja have won all four of their group games, scoring 12 goals, and lead England by three points, with the two sides meeting in Madrid on 15 November.
Spain's group run began with a 3-2 win at England on 26 September, followed by a 4-1 home win over Croatia, the 3-1 victory over Czechia in Oviedo and a 2-1 win at Croatia on 6 October.
La Roja's only clean sheet in the last five games came in the World Cup final, a 1-0 win over Argentina after extra time on 19 July.
That September win at England also gives the leaders the advantage in the head-to-head tie-break if the two sides finish level on points.
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Team news and predicted lineups for Czechia vs Spain
Czechia team news
Denia has confirmed that all 24 called-up players have medical clearance, although Adam Hlozek missed his last club match with an injury and is expected to be fit.
Robin Hranac, Ondrej Kricfalusi, Ondrej Lingr, Matej Rynes and Pavel Sulc are injured and Michal Sacek has a muscle problem, while Tomas Chory is not with the squad.
Michal Sadilek is reported to be suspended after yellow cards against Spain and England in October, while captain Ladislav Krejci returns after serving his ban for the red card in Oviedo.
Idris Hopi, 18, and David Kozel are the uncapped additions, while Tomas Soucek is back in the squad.
Antonin Kinsky is expected in goal, with Krejci back in central defence and Hlozek leading the line in a 4-2-3-1.
Czechia predicted lineup vs Spain
Kinsky; Coufal, Chaloupek, Krejci, Slama; Kral, Soucek; Cerv, Ambros, Danek; Hlozek
Spain team news
Without Lamine Yamal and Mikel Oyarzabal, Ferran Torres is expected to lead the line, with Nico Williams, Fermin Lopez and Alex Baena in the three behind him.
Pedro Porro is back from injury and expected at right-back, with Pau Cubarsi and Aymeric Laporte in central defence, Marc Cucurella at left-back and Unai Simon in goal.
Rodri, Dani Olmo and Eric Garcia were not selected through physical issues, Jorge de Frutos replaces the injured Ander Barrenetxea, and Victor Munoz was added to the squad on 9 November.
Baena and Lopez are each one booking from a ban for the England game, and both are expected to start in Prague.
Spain predicted lineup vs Czechia
Simon; Porro, Cubarsi, Laporte, Cucurella; Pedri, Ruiz; Williams, Lopez, Baena; Torres
Ruiz
Lopez
Head-to-head record between Czechia and Spain
La Roja have never lost to the Czechs since Czechia became independent, winning six of the eight meetings and drawing two, with 13 goals scored to four conceded.
The two managers have already met once as head coaches, and the world champions won that game 3-1 in Oviedo on 3 October, with Yamal scoring after six minutes and Rodri adding a second before half-time.
A Czechia goal from Ryan Naderi in the 79th minute was ruled out for an earlier foul in attack, and Krejci was sent off in the 85th minute for a second yellow card.
The last meeting in Prague was a 2-2 draw in June 2022, with Inigo Martinez equalising for the Spaniards in the 90th minute, and Czechoslovakia's last win over Spain came in November 1990.
Our Czechia vs Spain prediction and betting tips
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Odds correct as of Wednesday, 11 November 2026, 14:19 GMT.
- Torres leads Spain's line in the predicted XI and has seven goals this season
- Slama scored in Oviedo and is one of only two Czechia scorers in the group
- Hlozek leads the Czechia attack and is expected to be fit after missing his last club match
Adeyeye Oluwapelumi is a sports writer with more than 1,000 published articles covering football and major sporting events worldwide. His knowledge spans leagues across the globe, including the Premier League, La Liga, Serie A, Bundesliga and Ligue 1. Combining research, insight and creativity, he enjoys finding fresh angles and delivering engaging coverage of the game's biggest stories.