Old Trafford, Manchester
Saturday 10 October 2026, 17:30 BST
Manchester United, unbeaten in their last two meetings with Spurs, host Old Trafford's visitors sitting eight places and three points above them in 12th, and a repeat of February's 2-0 win at this ground would stretch Tottenham's winless run in the league to six games.
Tottenham arrive on the back of their worst start to a Premier League season on record, taking two points from their opening five matches under new head coach Roberto De Zerbi.
Man Utd vs Tottenham: form guide and preview
Manchester United sit eight places and three points better off in 12th, but their underlying form is sturdier than the table suggests.
Michael Carrick's side have won one, drawn two and lost two of their last five across all competitions, scoring nine and conceding seven, including a comfortable 4-0 Champions League win over Sabah FK sandwiched between a 2-2 league draw with Everton and a 1-0 league defeat to Manchester City.
They head into the weekend with Kobbie Mainoo in contention again after sitting out the international break through workload management rather than injury, a boost in central midfield for a side that has drawn two of its last three Premier League matches.
Carrick's bigger concern is at the back, where Matthijs de Ligt remains out following back surgery and Luke Shaw has carried a knock into the weekend, leaving a makeshift defence to face a Tottenham attack that has scored in just two of its last five outings.
No side in the Premier League has taken fewer points than Tottenham's two from their opening five games, and Opta rate it the club's worst start to a league campaign on record.
They have won none of their last five matches in all competitions, drawing twice and losing three times, scoring just three goals and conceding eight, with only two clean sheets to show for it.
De Zerbi, appointed at the end of March, is still searching for the defensive solidity that defined his best work at previous clubs, and Saturday's trip pits his side against a Manchester United attack that has found the net in five of its last six matches.
Tottenham's build-up has also been complicated off the pitch: Richarlison has not featured in a single Premier League squad this season after being left out of the club's 25-man list from the opening weekend, a situation that has continued into this international break.
Team news and predicted lineups: Man Utd vs Tottenham
Manchester United team news
Carrick's defensive options are stretched, with de Ligt still working his way back from surgery and Shaw managing discomfort of his own, leaving Harry Maguire and Lisandro Martinez as the settled centre-back pairing.
In midfield, Kobbie Mainoo is expected to return having missed England duty for workload reasons rather than injury, while Youri Tielemans is set to continue alongside him with Ugarte still out long-term.
Rashford's involvement is the biggest doubt in attack after the knock he took against Fulham, but the winger is expected to be fit in time for this one.
Carlos Baleba, a minor doubt of his own after an ankle issue, remains an option for Carrick off the bench in midfield.
Man Utd predicted lineup vs Tottenham
Predicted XI (4-2-3-1): Lammens; Dalot, Maguire, Martinez, Shaw; Tielemans, Mainoo; Mbeumo, Fernandes, Rashford; Cunha.
Tottenham team news
Tottenham's injury list is dominated by attackers, with Mudryk and Odobert both missing and Kulusevski nowhere near full fitness, leaving De Zerbi short of options to freshen up a front line that has misfired all season.
Micky van de Ven looks set to return at centre-back after a minor hand injury picked up on international duty, with Dutch staff describing the knock as nothing serious.
Van Hecke's own fitness is a closer call, with Marcos Senesi or Tosin Adarabioyo waiting to partner van de Ven if he fails to recover in time.
Porro's continued absence at right-back is the clearest marker of Tottenham's defensive problems, with the Spaniard not due back until nearer the Chelsea game later in October.
Tottenham predicted lineup vs Manchester United
Predicted XI (4-2-3-1): Kinsky; Gray, Senesi, van de Ven, Udogie; Tonali, Bentancur; Savio, Kudus, Marmoush; Solanke.
Head-to-head: Man Utd vs Tottenham
Manchester United's all-time advantage across 207 matches in all competitions is built on a different kind of fixture to the one these two clubs have played out most recently.
Tottenham have actually won three of the last five meetings between the sides, including a 4-3 EFL Cup win in December 2024 and United's Europa League final defeat to Spurs in Bilbao at the end of the 2024/25 season.
United's response has come at Old Trafford itself, though, winning February's Premier League meeting 2-0 and drawing 2-2 away at Tottenham the previous November.
Only one of the last five meetings was played at Old Trafford, and United won it, a detail that matters given how reliant Tottenham's recent head-to-head success has been on cup competition and a neutral venue rather than this fixture specifically.
Our Man Utd vs Tottenham prediction and betting tips
Odds correct as of Friday, 9 October 2026, 18:00 BST.
- Likely scorers for United: Bruno Fernandes, Bryan Mbeumo
- Matheus Cunha to add a third
- Tottenham response: Mateus Fernandes