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Lovely backheel from Johnson to set up a Downing cross but Lombaerts blocks; Downing recovers the ball though to win a throw. Fresh start from the Reds.
Suarez almost sends Lucas in but a good interception from Neto.
Semak, who made a goalscoring cameo in the first leg, drills a weak shot well wide. Then Enrique sends a long ball for Suarez, who almost does what he did against Newcastle but his touch takes it to Malafeev.
Gerrard releases Johnson down the right but the full-back Hubocan clears.
The first half is underway at Anfield. Can they pull off what should be considered an upset?
The bookies' odds to qualify: Liverpool 11/4, Zenit 1/4 - Brendan Rodgers' men are up against it, but this is far from mission impossible.
Tottenham and Newcastle are both through to the last 16 after the early games - can Chelsea and Liverpool join them?
Huge excitement in the early games - Tottenham on the brink of the last 16 thanks to a stunning late goal from Mousa Dembele.
Liverpool have fielded a strong side for this game. They are without the cup-tied Philippe Coutinho and Daniel Sturridge, and Martin Skrtel is still out. But otherwise they are pretty much at full strength.
It's a busy night of action in the Europa League, and we have already seen holders Atletico Madrid go out to Rubin Kazan, 2-1 on aggregate.
Midfielder Lucas Leiva has called on the Liverpool fans to lift their tream to victory tonight: "Hopefully the crowd will give us a special night and we will play well and get through. The crowd will definitely be our 12th player."
Liverpool have a mountain to climb tonight. Despite producing what Brendan Rodgers described as a "near-perfect" away performance, they went down 2-0 in the away leg and face a tough job clawing it back.
LIVERPOOL: Reina, Johnson, Enrique, Agger, Carragher, Lucas, Allen, Gerrard, Henderson, Downing, Suarez.... Subs: Gulacsi, Coates, Wisdom, Shelvey, Assaidi, Suso, Sterling. // ZENIT: Malafeev, Anyukov, Lombaerts, Neto, Hubocan, Shirokov, Semak, Denisov, Witsel, Danny, Hulk... Subs: hevnov, Alves, Criscito, Rodic, Fayzulin, Bukharov, Kerzhakov.