Hello and welcome to LIVE updates of runaway leaders Manchester City's clash with Tottenham at the Etihad Stadium. The Citizens are targeting a 16th straight league victory that would see them move 14 points clear of second-placed Manchester United, who are not in action until Sunday at West Brom. Kick off 17:30 GMT.

First moment of danger in the final third and it's City who go close. Sane dazzles Trippier and surges to the left byline before fizzing in a low ball that Vertonghen beats Aguero to. Super defending.

DID YOU KNOW? Aguero has notched 35 times in 52 Premier League games against the big six. A man who likes the big occasion.

Even stevens so far.

Spurs pressing and hounding the City players hungrily in the early exchanges.

So, Guardiola aiming for a 16th straight league success that would match the tally of his best run at Barcelona in 2010-11. However, they still have work to do to surpass his best ever sequence of 19 league victories on the spin with Bayern Munich in 2013-14.

DID YOU KNOW? Spurs have picked up just one victory in 17 PL away games against the 'big six' under Poch. They have lost 10 of those, but that solitary success did come at the Etihad in February 2016.

KICK OFF! City get us underway.

Harry Kane is also chasing a significant milestone. The England striker has fired 33 goals in 33 games for Spurs in 2017 and is chasing Alan Shearer's record of 36 in a calendar year, that was set back in 1995. Kane has three games - including this one - to find four more. He also has matches against Burnley away and Southampton at home.

WILL IT BE TON UP FOR SERGIO? Aguero is one away from netting 100 goals for Manchester City at the Etihad Stadium in all competitions. He has 99 in 133 home matches.

HEAD-TO-HEAD: The Citizens have not beaten the Lilywhites in five matches (drawn 1, lost 3). Indeed, Spurs seem to enjoy visits to City, having clocked up their highest tally of PL away wins there (10).

Raheem Sterling: "Harry (Kane), Dele (Alli) that I play with, they are ruthless and also Son (Heung-min) - these are massive players that they have, so it will be a massive game."

Meanwhile, Guardiola has responded Jose Mourinho's claim that Manchester City are prepared to commit 'tactical fouls'.

Mauricio Pochettino: "We're going to enjoy it, because it's a fantastic challenge to play against Manchester City. They're the best team in England and one of the best in Europe."

Spurs are unbeaten in four in all competitions after a mini blip in November that started with a 2-0 loss in the North London derby on November 18. The Lilywhites went four PL matches without a win - losing twice along the way - before getting back on track with a 5-1 rout of Stoke last weekend. A 2-0 midweek success over Brighton brings them into this test in improving form and Mauricio Pochettino has made three changes with Kieran Trippier, Mousa Dembele and Dele Alli coming into the starting XI.

BLOW FOR CITY, BOOST FOR SPURS? The big news relating to the teamsheet is that David Silva is not involved for the hosts due to 'personal reasons.' Pep Guardiola makes three changes from the win over Swansea with Kyle Walker, Ilkay Gundogan and Leroy Sane coming in.

CONFIRMED TEAMS - MAN CITY: Ederson, Walker, Otamendi, Mangala, Delph, De Bruyne, Fernandinho, Gundogan, Sane, Sterling, Aguero... Subs: Bravo, Yaya Toure, Foden, G Jesus, Bernardo, Zinchenko, Danilo. /// SPURS: Lloris, Trippier, Dier, Vertonghen, Rose, Dembele, Winks, Eriksen, Dele, Son, Kane... Subs: Vorm, Aurier, Davies, Foyth, Sissoko, Lamela, Llorente.