| 1 | Karim Benzema
Real Madrid | Real Madrid | 32 | 27 |
| 2 | Iago Aspas
RC Celta | RC Celta | 37 | 18 |
| 3 | Vinícius Júnior
Real Madrid | Real Madrid | 35 | 17 |
| - | Raúl De Tomás
RCD Espanyol | RCD Espanyol | 34 | 17 |
| 5 | Juanmi
Real Betis | Real Betis | 33 | 16 |
| - | Enes Ünal
Getafe CF | Getafe CF | 37 | 16 |
| 7 | Joselu
Deportivo Alavés | Deportivo Alavés | 37 | 14 |
| 8 | José Luis Morales
Levante UD | Levante UD | 35 | 13 |
| 9 | Memphis Depay
FC Barcelona | FC Barcelona | 28 | 12 |
| - | Ángel Correa
Atlético Madrid | Atlético Madrid | 36 | 12 |
| 11 | Pierre-Emerick Aubameyang
FC Barcelona | FC Barcelona | 17 | 11 |
| - | Luis Suárez
Atlético Madrid | Atlético Madrid | 35 | 11 |
| - | Carlos Soler
Valencia CF | Valencia CF | 32 | 11 |
| - | Gonçalo Guedes
Valencia CF | Valencia CF | 36 | 11 |
| 15 | Arnaut Danjuma
Villarreal CF | Villarreal CF | 23 | 10 |
| - | Borja Iglesias
Real Betis | Real Betis | 33 | 10 |
| - | Marco Asensio
Real Madrid | Real Madrid | 31 | 10 |
| - | Rafa Mir
Sevilla FC | Sevilla FC | 34 | 10 |
| - | Jorge Molina
Granada CF | Granada CF | 35 | 10 |
| 20 | Gerard Moreno
Villarreal CF | Villarreal CF | 17 | 9 |
| - | Mikel Oyarzabal
Real Sociedad | Real Sociedad | 22 | 9 |
| 22 | João Félix
Atlético Madrid | Atlético Madrid | 24 | 8 |
| - | Willian José
Real Betis | Real Betis | 32 | 8 |
| - | Pere Milla
Elche CF | Elche CF | 32 | 8 |
| - | Sergi Guardiola
Rayo Vallecano | Rayo Vallecano | 32 | 8 |
| - | Ante Budimir
CA Osasuna | CA Osasuna | 28 | 8 |
| - | Iñaki Williams
Athletic Club | Athletic Club | 38 | 8 |
| - | Luis Suárez
Granada CF | Granada CF | 37 | 8 |
| 29 | Anthony Lozano
Cádiz CF | Cádiz CF | 31 | 7 |
| - | Gonzalo Melero
Levante UD | Levante UD | 29 | 7 |
| - | Lucas Boyé
Elche CF | Elche CF | 24 | 7 |
| - | Hugo Duro
Valencia CF | Valencia CF | 30 | 7 |
| - | Roger
Levante UD | Levante UD | 29 | 7 |
| - | Álvaro Negredo
Cádiz CF | Cádiz CF | 34 | 7 |
| - | Santi Mina
RC Celta | RC Celta | 33 | 7 |
| - | Álvaro García
Rayo Vallecano | Rayo Vallecano | 36 | 7 |
| 37 | Luuk de Jong
FC Barcelona | FC Barcelona | 21 | 6 |
| - | Radamel Falcao
Rayo Vallecano | Rayo Vallecano | 22 | 6 |
| - | Borja Mayoral
Getafe CF | Getafe CF | 18 | 6 |
| - | Matheus Cunha
Atlético Madrid | Atlético Madrid | 29 | 6 |
| - | Oihan Sancet
Athletic Club | Athletic Club | 27 | 6 |
| - | Yéremi Pino
Villarreal CF | Villarreal CF | 31 | 6 |
| - | Raúl García
Athletic Club | Athletic Club | 35 | 6 |
| - | Luis Avila
CA Osasuna | CA Osasuna | 36 | 6 |
| - | Lucas Ocampos
Sevilla FC | Sevilla FC | 30 | 6 |
| - | Alexander Isak
Real Sociedad | Real Sociedad | 32 | 6 |
| - | Manu Trigueros
Villarreal CF | Villarreal CF | 35 | 6 |
| - | Antonio Puertas
Granada CF | Granada CF | 33 | 6 |
| - | Yannick Carrasco
Atlético Madrid | Atlético Madrid | 34 | 6 |
| - | Nabil Fekir
Real Betis | Real Betis | 34 | 6 |