Man United draw Saints

Holders Portsmouth will host Bristol City at Fratton Park while there are three all-Premier League ties: Sunderland against Bolton, Hull City at home to Newcastle and Wigan's visit to Tottenham.

Giant killers Barnsley, vanquishers of Liverpool and Chelsea last season, will travel to West Ham United.

Village side Histon, second in the Blue Square Premier and who beat Leeds 1-0 in the second round, will welcome Swansea City to their home ground.

Another club from the division below the Football League, Barrow, have been drawn away to top flight outfit Middlesbrough.

Blue Square North side Droylsden will play away at Ipswich if they get past Chesterfield.

In the other ties featuring non-league sides, Forest Green Rovers are at home to Derby County, Kettering Town and Eastwood Town will play each other if Kettering beat Notts County in a replay, Kidderminster Harriers travel to Coventry and Blyth Spartans have the carrot of a home match with Blackburn Rovers if they can dump out Bournemouth.

Portsmouth v Bristol City

Sheffield Wednesday v Fulham

Preston North End v Liverpool

Birmingham City v Wolverhampton Wanderers

West Ham United v Barnsley

Middlesbrough v Barrow

Hull City v Newcastle United

Hartlepool United v Stoke City

Chelsea v Southend United

Manchester City v Nottingham Forest

Cardiff City v Reading

Ipswich Town v Chesterfield or Droylsden

Charlton Athletic v Norwich City

West Bromwich Albion v Peterborough United or Tranmere Rovers

Torquay United v Blackpool

Leyton Orient v Sheffield United

Southampton v Manchester United

Millwall v Crewe Alexandra

Histon v Swansea City

Forest Green Rovers v Derby County

Queens Park Rangers v Burnley

Leicester City v Crystal Palace

Tottenham Hotspur v Wigan Athletic

Cheltenham Town v Doncaster Rovers

Arsenal v Plymouth Argyle

Notts County or Kettering Town v Eastwood Town

Bournemouth or Blyth Spartans v Blackburn Rovers

Macclesfield Town v Everton

Watford v Scunthorpe United

Sunderland v Bolton Wanderers

Coventry City v Kidderminster Harriers

Gillingham or Stockport County v Aston Villa