Benfica in good shape

Meanwhile Lyon, hoping to qualify for the 12th time in succession, conceded an early goal before beating Russian visitors Rubin Kazan 3-1.

Viktoria Plzen have a great chance of qualifying for the first time after a 3-1 win at FC Copenhagen while Austrian title holders Sturm Graz held Belarus champions BATE Borisov 1-1 away.

Benfica, who despite winning the old European Cup twice and finishing runners-up five times have made only a modest six Champions League appearances, were denied an away win when Costa Rican Bryan Ruiz scored an 80th minute goal for Twente.

The Dutch side had taken a sixth-minute lead through Luuk de Jong before Oscar Cardozo, with a curling shot, and Nolito put the Portuguese 2-1 ahead at halftime.

Rubin Kazan took a third-minute lead at Lyon through Vladimir Dyadyun but the French replied within seven minutes through Bafetimbi Gomis and a Solomon Kverkvelia own goal put them ahead five minutes before the break.

Jimmy Briand added another midway through the second half.

Solvi Ottesen scored at both ends as Copenhagen, who reached the last 16 last season, were stunned by the Czech champions.

He turned the ball into his own net to give Plzen the lead in the 52nd minute and Vaclav Pilar fired home the second seven minutes later.

Ottesen made amends by heading home for the Danes in the 69th minute but Martin Fillo curled in a superb third for Plzen 10 minutes later.

Sturm Graz, who last qualified in 2000/01, went ahead when Manuel Weber provided a clinical finish to a counter-attack in the 12th minute.

They should have scored again before halftime when Milan Dudic, unmarked and four metres from goal, failed to connect with Andreas Hoelzl's free kick.

The hosts, who had much more possession, levelled with a Marko Simic header just before the hour.

Five more play-off matches are scheduled for Wednesday, including four-times European champions Bayern Munich against FC Zurich, with the second legs to be played next week.